ADAGENE PRESENTS CLINICAL DATA DEMONSTRATING STRONG SAFETY AND EARLY SIGNALS OF EFFICACY IN COLD TUMORS INCLUDING PANCREATIC AND OVARIAN CANCERS FOR ANTI-CTLA-4 MONOCLONAL ANTIBODY, ADG116, AT ESMO-IO 2021

Additional highlights include pharmacodynamic biomarker analyses from ongoing trial of anti-CD137 antibody, ADG106, in combination with anti-PD-1 toripalimab

SAN DIEGO and SUZHOU, China, Dec 7 (Bernama-GLOBE NEWSWIRE) -- Adagene Inc. (“Adagene”) (Nasdaq: ADAG), a platform-driven, clinical-stage biopharmaceutical company committed to transforming the discovery and development of novel antibody-based immunotherapies, today announced clinical data on its anti-CTLA-4 monoclonal antibody, ADG116, and anti-CD137 agonist, ADG106, in two poster presentations at the European Society for Medical Oncology Immuno-Oncology (ESMO-IO) Congress 2021, to be held virtually and in Geneva, Switzerland from December 8 to 11, 2021. Both posters are available in the Publications section of the company’s website at www.adagene.com.

In the first presentation of results from an ongoing dose-escalation trial of monotherapy in patients with advanced metastatic tumors, ADG116 demonstrated a strong safety profile and early signals of efficacy, including dose-dependent T-cell activation and tumor suppression in treatment-resistant “cold” and “warm” tumors such as pancreatic, ovarian and renal cell cancers.

Commenting on the findings, Dr. Gary Richardson, OAM, MBBS, FRACP, Group Director at Cabrini Health Research, Director at Szalmuk Family Department of Medical Oncology and Professor of Medicine at Monash University, Australia, “These encouraging clinical data demonstrate the promising safety profile of ADG116 monotherapy in patients with advanced solid tumors across 15 different tumor types, the majority of which are resistant to standard therapy. The most exciting thing about these results is that we have also seen the early signals of efficacy in ‘cold’ tumors such as pancreatic and certain gynecological cancers, which do not respond to current immunotherapies. We want to see this type of unique activity, which suggests that this treatment may look different and potentially better than the options we have available today.”

Additionally, a separate poster presentation describing results of pharmacodynamic (PD) biomarker analyses reinforced the synergy and strong T-cell activation of ADG106 in combination with the anti-PD-1 antibody toripalimab.
 
A summary of data from both posters is included below. 

http://mrem.bernama.com/viewsm.php?idm=41831

UMICORE, VOLKSWAGEN AG TO FUEL JOINT-VENTURE SUPPLYING EUROPEAN EV BATTERY MATERIALS

KUALA LUMPUR, Dec 9 (Bernama) -- Umicore and Volkswagen AG plan to establish a joint venture to build up precursor and cathode material production capacities in Europe to supply Volkswagen AG’s European battery cell production, making a considerable contribution to the region’s transition towards cleaner mobility.

This partnership will be the first of its kind in the European automotive market, helping achieve the ambitions of the European Green Deal, including establishment of a sustainable battery supply chain, and is a strong signal for the ongoing roll-out of innovative battery cell technologies and capabilities in the region.

The intention is to gradually ramp up the JV’s precursor and cathode material production capacity. This would start in 2025 with an initial annual production of 20 GWh for Volkswagen AG’s plant in Salzgitter, Germany, and should grow to an annual production capacity of up to 160 GWh by the end of the decade.

This compares to an annual production capacity capable of powering about 2.2 million full electric vehicles (EVs).

At the same time, next to the intended JV, Umicore will continue to steadfastly develop its technological and production capabilities to serve other customers and regions.

“As a leader in clean mobility materials, we are committed to support our automotive and battery-cell customers with their electrification strategies. We are very pleased to partner with Volkswagen in this unique joint venture and will bring in our long-standing and proven expertise in battery materials, as well as our strong commitment and solutions to today’s sustainability challenges,” said Umicore CEO, Mathias Miedreich in a statement.

 Thomas Schmall, Member of the Board of Management of Volkswagen Group for Technology and CEO of Volkswagen Group Components said: “Teaming up with Umicore enables us to establish a state-of-the-art supply chain in Europe as we share common values such as responsible sourcing of raw materials, as well as closed-loop thinking.”

The partnership’s significant scale will provide secure and cost-competitive supplies of innovative, sustainably sourced and tailored high-performance cathode materials for Volkswagen AG’s ambitious unified cell strategy. It provides Umicore secured access to an important part of the European demand for EV cathode materials.

In the context of the JV, Umicore and Volkswagen AG will furthermore collaborate on the sustainable and responsible sourcing of raw materials, which is a strong area of expertise of Umicore. Both parties aim to include at a later stage, elements of refining and battery recycling into the scope of the JV.

The planned JV is subject to final agreements and customary conditions, including regulatory approvals.

-- BERNAMA

NIKKISO CLEAN ENERGY & INDUSTRIAL GASES GROUP IN UNITROVE LIQUID HYDROGEN BUNKERING INSTALLATION

KUALA LUMPUR, Dec 8 (Bernama) -- Nikkiso Cryogenic Industries’ Clean Energy & Industrial Gases Group (Group), a subsidiary of Nikkiso Co Ltd (Japan), has announced participation in the bunkering installation design of a new complete Liquid Hydrogen (LH₂) Bunkering installation with Unitrove.

Nikkiso CE&IG and Unitrove are working together to develop solutions for the future, particularly regarding LH2.

For this project, the Group provided custom equipment from two of its Functional Units: a sump from its Heat Exchangers unit (Cryoquip) and Cryogenic Pumps unit (ACD).

“We are excited and proud to be part of one of the world’s first liquid hydrogen (LH₂) bunkering facility projects and the drive toward more energy-efficient solutions for the Marine market,” according to Ole Jensen, Vice President, Europe, Nikkiso Clean Energy & Industrial Gases Group.

The Bunkering system is being showcased at the United Nations COP26 Environmental Conference in Glasgow, which runs through Nov 12. The installation is expected to be completed sometime in 2022.

According to a statement, this will be the first of several expected projects to be delivered in 2022.

Cryogenic Industries Inc (now a member of Nikkiso Co Ltd) member companies manufacture engineered cryogenic gas processing equipment and small-scale process plants for the liquefied natural gas (LNG), well services and industrial gas industries.

Cryogenic Industries is the parent company of ACD, Cosmodyne and Cryoquip and a commonly controlled group of approximately 20 operating entities.

For more information, visit www.nikkisoCEIG.com.

-- BERNAMA

LANTRONIX NAMED QUALCOMM AUTOMOTIVE SOLUTIONS ECOSYSTEM PROGRAM MEMBER

KUALA LUMPUR, Dec 8 (Bernama) -- Lantronix Inc, a global provider of secure turnkey solutions for the Intelligent IT and the Internet of Things (IoT), has announced being named member of the Qualcomm® Authorized Design Center Program’s automotive program.

A long-time Qualcomm® Advantage Network member, Lantronix joined the invitation-only program, which assists companies in accelerating innovation by connecting customers with an ecosystem of businesses that provide tools and deep expert design services.

Lantronix will participate in the automotive program, referred to as the Qualcomm® Automotive Solutions Ecosystem Program, by providing access to tools that are built around the 3rd Generation Snapdragon® Automotive Cockpit Platform, a product of Qualcomm Technologies, Inc.

“We are proud to be named a member of the Qualcomm Authorized Design Center’s Automotive Solutions Ecosystem Program, which will bring engineering and design expertise to our mutual customers while helping fast-track innovation,” said Lantronix CEO, Paul Pickle in a statement.

“With the program, Lantronix is positioned to accelerate the commercialisation of automotive products, which will include customisation, optimisation and other design and integration services built around the 3rd Generation Snapdragon Automotive Cockpit Platforms.”

The 3rd Generation Snapdragon Automotive Cockpit Platforms are artificial intelligence (AI)-based and some of the most advanced automotive platforms from Qualcomm Technologies.

Lantronix’s inclusion in the Qualcomm Automotive Solutions Ecosystem Program, as well as its team’s proven expertise and collaboration over the years, reinforces its commitment to providing cutting-edge development services with Qualcomm Technologies for its global customers focused on the Snapdragon Automotive Cockpit platform.

-- BERNAMA

I2C SETS INDUSTRY RECORD WITH MORE THAN 20 NEW IMPLEMENTATIONS ACROSS 10 MARKETS IN NOVEMBER

Global payments and digital banking leader reports strong global demand for its services with another 50 new implementations slated to be completed before Q1 2022


REDWOOD CITY, Calif., Dec 8 (Bernama-BUSINESS WIRE) -- i2c Inc., a leading provider of digital payment and banking technology, today announced it had deployed more than 20 new payment and digital banking programs for clients across 10 markets and four continents during the month of November alone.

“The growth levels combined with the diversity of customers and programs we’re witnessing in our business today is a testament to our growth strategy and global team,” said Amir Wain, founder and CEO of i2c Inc. “We are thrilled to be the enabler of choice for visionaries in the payments and digital banking space as they work to accelerate financial innovation and expand access to millions of end users worldwide,” he said.

i2c powers industry leaders in fintech, digital banking, cryptocurrency, as well as traditional financial institutions on a single, agile global platform. This fiscal half’s success includes new enterprise partners, as well as product and global program expansions for several U.S. and international programs, including: 1derful (Australia), BEYON Money (Bahrain), Caary (Canada), Crypto.com (Brazil), Standard International Bank (Puerto Rico), Solid (USA) and TAG (Pakistan).

i2c powers a deep range of payment products and services from debit and prepaid cards to lending (both consumer and commercial credit, as well as BNPL and LOC), featuring access to every major network partner (American Express, Discover, Mastercard, Visa, and Union Pay). Additionally, the company provides partners value-added banking and payment services such as fraud prevention, contact center, dispute management, as well as white-label web and mobile apps.

About i2c Inc.

i2c is a global provider of highly-configurable payment and banking solutions. Using i2c's proprietary "building block" technology, clients can easily create and manage a comprehensive set of solutions for credit, debit, prepaid, lending and more, quickly and cost-effectively. i2c delivers unparalleled flexibility, agility, security and reliability from a single global SaaS platform. Founded in 2001, and headquartered in Silicon Valley, i2c's next-generation technology supports millions of users in more than 200 countries/ territories and across all time zones. For more information, visit www.i2cinc.com and follow us at @i2cinc.

View source version on businesswire.com: 
https://www.businesswire.com/news/home/20211207005335/en/

Contact

Heather Clifton
Chief Marketing Officer
media@i2cinc.com

Source : i2c Inc.

Unify Platform AG Starts New Feature On Company's Online Platform UNIPLAT

KUALA LUMPUR, Nov 30  -- Unify Platform AG of Switzerland, with its Japan Hub in Shin-Yokohama, Kanagawa Prefecture, has announced the launch of a new feature on the company's online platform service, UNIPLAT.

According to a statement, the new feature is Credit Rating: an automatic performance rating of each researcher and entrepreneur on UNIPLAT, evaluated from various perspectives using AI.

The evaluation result is displayed as credit scores. If the scores are high, the relevant researcher's capability and credibility are also considered high. This Credit Rating will be available on the platform, beginning Dec 23.

The credit scores of a researcher or entrepreneur can be viewed on their ‘My Lab’ page (a one-stop page that contains their profile, result of research, and other information. My Lab will be launched at the same time as Credit Rating).

The scores are set to be visible to the public. So, general users -- individuals, companies, or research institutions -- can check the researcher or entrepreneur's capability and credibility to ascertain their choice of support or research collaboration. Talking from the researcher and entrepreneur's side, this feature could open the door to many benefits such as offers and grants from companies and institutions.

Currently, the aspects scored by Credit Rating's AI are, number of likes of each content (live streaming, videos, and documents); number of each content's views; and, number of connections (primary nodes).

The scoring aspects and formulas are subject to refinement in a once-a-year credit rating evaluation committee meeting, following changes in global academic circumstances.

UNIPLAT is an open platform specifically designed to help entrepreneurial researchers who promote all academic fields and projects related to the SDGs advocated by the United Nations worldwide to obtain more exposure and connect with supporters who want to contribute to the improvement of global research.

-- BERNAMA

DEVELOPMENT CONTINUES ON REAL REALM (RISE STUDIO)! POST IDO UPDATES AND UPCOMING GATE.IO LISTING

SINGAPORE, Dec 2 (Bernama-GLOBE NEWSWIRE) -- Real Realm (Rise Studio) has successfully completed its IDO on Kardiachain and BSC station. There was a huge demand once the sale has started and shortly after a while all the Real Tokens were sold.

Amazingly all-time high price was 72x higher than IDO price and the current price is around 30x higher than it. The community was satisfied with the results.

If you don’t know what Real Token is, here quick summary for you:

The Real Token is the governance token in Real Realm. Strong Holders of the Real tokens are able to shape and vote for the future direction of the game universe while earning from the Staking feature.

In addition to the governance function, the Real tokens are also used for trading in the Marketplace and recruiting high-class Mies.

Upcoming Developments

Now, after the IDO upcoming developments are coming quickly to the Real Realm. New listings, staking options, partnerships are going to create huge interest in the project.

The first NFT listing is coming on DareNFT

Real Realm NFTs will be listed on DareNFT in the first week of December.

Users who've successfully joined the "NFT whitelist" will have priority to purchase hero boxes on DareNFT and will have a chance to add a variety of amazing Real Realm NFT's to their portfolio.

Ready to be listed on Gate.io

Photo: https://www.globenewswire.com/NewsRoom/AttachmentNg/36d766e7-9587-4527-8963-83504a8a8452 

This is one of the important updates from the project coming on the 1st Dec. $REAL tokens will be listed on Gate.io, one of the most popular crypto exchanges.

Since Gate.io will be the first CEX exchange that $REAL token will be listed. That will give users more options to buy and sell $REAL tokens easily.

Trading Time: 3AM Dec 2nd, 2021

The Game Continues to Develop Without Slowing Down

It has been just more than a month since Real Realm started to being developed. However, over the past weeks, there were countless partnership deals, publications, updates on the game side. So it seems that will cause big hype once the game is launched next month in December. Users are so excited about the upcoming updates.

Don’t forget to follow us on social media:

Website: https://realrealm.io/
Twitter: https://twitter.com/RealRealmGame
Telegram Group: t.me/realrealmofficial
Telegram Channel: t.me/realrealmannouncement
Facebook: https://www.facebook.com/RealRealmGlobal/
Discord: https://discord.com/invite/6r4HfPXc


Ms. Khanh Pham
CMO, Real Realm
Khanhpl@risestudio.me 

Source: RISE STUDIO PTE.LTD

--BERNAMA